Journal of Psychiatry and Psychiatric Disorders

ISSN: 2572-519X
Impact Factor: 1.9
Index Copernicus Value: 70.80
Abstracting and Indexing

Editor In Chief

Michael Maes

Molecular Biology and Neuroscience
Deakin University
Victoria, Australia



Effects of Sleep Deprivation on Brain Functional Network

Background: Sleep deprivation adversely affects the brain and cognitive function. Few studies have analyzed effect of the sleep deprivation and partial sleep restriction on rest-state brain functional network.

Method: In this study, we investigated the changes of rest-state functional magnetic resonance imaging (fMRI) in topological architectures of brain functional networks in sleep deprivation among 36 samples in sleep deprivation and 40 normal sleep controls.

Result: Our analysis revealed that the brain functional network of the clustering coefficient, characteristic path length and local efficiency are significantly increased but the global efficiency decreased significantly in sleep deprivation. Additionally, significant alterations in nodal efficiency were also found in sleep deprivation, involving anterior cingulate, inferior parietal, supramarginal gyrus, caudate nucleus, thalamus are significant decreased, and themiddle temporal gyrus are significant increased.

Conclusion: Our results suggested that the groups of sleep deprivation were associated with disruptions in the topological structure of brain functional networks.


Ming Ye, ShuHui Tang, Peng Qing, Guangyuan Liu

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